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KMID : 0363619990200020063
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Journal of Korean Oriental Medicine
1999 Volume.20 No. 2 p.63 ~ p.74
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Effects of Moxibustion at the CV5(Serk-Moon) on the Expression of 3{beta}-Hydroxysteroid; dehydrogenasa/{Delta}5-{Delta}4 isomerase (3{beta}-HSD) in Ovary of the Rats
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Choi Young-Sun
Ahn Seong-Hun
Koo Sung-Tae
Lee Mun-Ho
Kim Kyung-Sik
Sohn In-Chul
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Abstract
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We demonstrated the moxibution on CV5(Serk-Moon) and CV3(Chung-Guk), as we have known contraceptive acupuncture point and pregnancy acupuncture point in oriental medcine, effected on concentration of progesteron and estrogen. As the reports, 3{beta}-hydroxysteroid;dehydrogenase/{Delta}5-{Delta}4 isomerase (3{beta}-HSD) is an enzyme that has catalytic oxidation and isomerase reaction on steroidhormon synthase including progesteron and estrogen. So we observated the concentration and mass of (3{beta}-HSD) by immuno-chemicalstain, western blot and Enzyme-Linked Immunosorbent Assay in rat ovary. In results, we detected that the mass of (3{beta}-HSD) decreased significantly in moxibution treated group on CV5(p{leq}0.05) in rat ovary and proposed that the moxibution of CV5 make possible to contraception because of blocking estrogen synthesis by (3{beta}-HSD) decrease. But we didn’’t know moxibution effects exactly whether is biochemical reaction or thermal reaction on acupuncture point.
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KEYWORD
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moxibustion, CV5(Serk-Moon), 3{beta}-HSD, contraception
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